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Watch Grey’s Anatomy Season 5 Episode 22 What a Difference a Day Makes Online

As Meredith, Derek and all of their friends prepare for the big wedding, a group of college students, injured in a car crash as they were heading to their graduation ceremony, is admitted to the ER. Meanwhile, Izzie fears the worst when she begins experiencing familiar symptoms. It turns out she has another brain tumor, which makes Derek and Meredith give their wedding to Izzie and Alex who get married instead.

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